Knockdown of PAF1 reduces cervical cancer cell proliferation, migration and invasion via retarding FLOT2-mediated MEK/ERK1/2 pathway

Knockdown of PAF1 reduces cervical cancer cell proliferation, migration and invasion via retarding FLOT2-mediated MEK/ERK1/2 pathway

ABSTRACTCervical cancer (CC) is a very usual reproductive malignant tumor in women. RNA polymerase II-associated factor 1 (PAF1) and flotillin-2 (FLOT2) both have been discovered to key participators in cancers’ progression. However, the effects of PAF1/FLOT2 axis on CC development have not been pro...

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Bibliographic Details
Main Authors: Bin Tang, Shulan Dou
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Cell Adhesion & Migration
Subjects:
Cervical cancer
FLOT2
MEK/ERK1/2 pathway
PAF1
proliferation
invasion
Online Access:https://www.tandfonline.com/doi/10.1080/19336918.2023.2260641

Internet

https://www.tandfonline.com/doi/10.1080/19336918.2023.2260641

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