NLRP3 inflammasome activation contributes to the cognitive decline after cardiac surgery

NLRP3 inflammasome activation contributes to the cognitive decline after cardiac surgery

BackgroundPerioperative neurocognitive disorders (PND) are a common complication of cardiac surgery in elderly patients. The etiopathogenesis of PND is not clear. Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, a macromolecular protein complex, regulates inflammation by indu...

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Bibliographic Details
Main Authors: Gang Ma, Ping Sun, Yi Chen, Xin Jiang, Caixia Zhang, Baofu Qu, Xiangkun Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Surgery
Subjects:
NLRP3 inflammasome
perioperative neurocognitive disorders (PND)
inflammation
interleukin - 1β
interleukin
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2022.992769/full

Internet

https://www.frontiersin.org/articles/10.3389/fsurg.2022.992769/full

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