Metabolic Pathways and Potencies of New Fentanyl Analogs

Metabolic Pathways and Potencies of New Fentanyl Analogs

Up to now, little is known about the metabolic pathways of new fentanyl analogs that have recently emerged on the drug markets worldwide with high potential for producing addiction and severe adverse effects including coma and death. For some of the compounds, limited information on the metabolism h...

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Bibliographic Details
Main Authors: Maurice Wilde, Simona Pichini, Roberta Pacifici, Adriano Tagliabracci, Francesco Paolo Busardò, Volker Auwärter, Renata Solimini
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Pharmacology
Subjects:
novel synthetic opioids
fentanyl analogs
fentanyl biotransformations
in vivo and in vitro metabolism
metabolic profile
receptor binding affinity
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00238/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.00238/full

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