Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia.

ROR1 is a receptor tyrosine kinase expressed in chronic lymphocytic leukemia (CLL) and several other malignancies but absent in most adult normal tissues. ROR1 is considered an onco-fetal antigen. In the present study we analysed spontaneous humoral and cellular immunity against ROR1 in CLL patients...

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Main Authors: Mohammad Hojjat-Farsangi, Mahmood Jeddi-Tehrani, Amir Hossein Daneshmanesh, Fariba Mozaffari, Ali Moshfegh, Lotta Hansson, Seyed Mohsen Razavi, Ramazan Ali Sharifian, Hodjattallah Rabbani, Anders Österborg, Håkan Mellstedt, Fazel Shokri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4642968?pdf=render