A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria.

A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria.

In Africa, infant susceptibility to Plasmodium falciparum malaria increases substantially as fetal hemoglobin (HbF) and maternal immune IgG disappear from circulation. During the first few months of life, however, resistance to malaria is evidenced by extremely low parasitemias, the absence of fever...

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Bibliographic Details
Main Authors: Chanaki Amaratunga, Tatiana M Lopera-Mesa, Nathaniel J Brittain, Rushina Cholera, Takayuki Arie, Hisashi Fujioka, Jeffrey R Keefer, Rick M Fairhurst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3075246?pdf=render

Internet

http://europepmc.org/articles/PMC3075246?pdf=render

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