Coverage statistics for sequence census methods

<p>Abstract</p> <p>Background</p> <p>We study the statistical properties of fragment coverage in genome sequencing experiments. In an extension of the classic Lander-Waterman model, we consider the effect of the length distribution of fragments. We also introduce a codi...

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Bibliographic Details
Main Authors: Evans Steven N, Hower Valerie, Pachter Lior
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/430