Development of DNA aptamer selection approach based on membrane ultrafiltration of aptamer/target complex

Background. Aptamers are small single-stranded DNA or RNA molecules that have an affinity for a specific target molecule. The main method of aptamers construction is the technology of systematic evolution of ligands with exponential enrichment (SELEX). However, the exact approach depends on the natu...

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Bibliographic Details
Main Authors: I. S. Solovarov, M. A. Khasnatinov, N. A. Liapunova, I. G. Kondratov, G. A. Danchinova
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2022-12-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/3888