Functional <i>ERAP1</i> Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of <i>HLA-B27</i> in Taiwanese

Functional <i>ERAP1</i> Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of <i>HLA-B27</i> in Taiwanese

Epistasis of <i>ERAP1</i> single nucleotide variations (SNVs) and <i>HLA-B27</i> has been linked to ankylosing spondylitis susceptibility (AS). The current study examined how prevalent <i>ERAP1</i> allelic variants (SNV haplotypes) in Taiwan affect ERAP1 functions...

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Bibliographic Details
Main Authors: Chin-Man Wang, Ming-Kun Liu, Yeong-Jian Jan Wu, Jing-Chi Lin, Jian-Wen Zheng, Jianming Wu, Ji-Yih Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
ankylosing spondylitis
ERAP1
single nucleotide variant
HLA-B27
HLA class I molecules
Online Access:https://www.mdpi.com/2073-4409/11/15/2427

Internet

https://www.mdpi.com/2073-4409/11/15/2427

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