Gleevec (STI-571) inhibits lung cancer cell growth (A549) and potentiates the cisplatin effect in vitro

<p>Abstract</p> <p>Background</p> <p>Gleevec (aka STI571, Imatinib) is a recently FDA approved anti-tumor drug for chronic myelogenous leukemia. Gleevec binds specifically to BCR-ABL tyrosine kinase and inhibit the tyrosine kinase activity. It cross-reacts with another...

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Bibliographic Details
Main Authors: Turner Steven, Ducatman Barbara S, Gao Wei, Zhang Peilin
Format: Article
Language:English
Published: BMC 2003-01-01
Series:Molecular Cancer
Subjects:
Online Access:http://www.molecular-cancer.com/content/2/1/1