Gleevec (STI-571) inhibits lung cancer cell growth (A549) and potentiates the cisplatin effect in vitro
<p>Abstract</p> <p>Background</p> <p>Gleevec (aka STI571, Imatinib) is a recently FDA approved anti-tumor drug for chronic myelogenous leukemia. Gleevec binds specifically to BCR-ABL tyrosine kinase and inhibit the tyrosine kinase activity. It cross-reacts with another...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2003-01-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://www.molecular-cancer.com/content/2/1/1 |