Surface Anchoring of the Kingella kingae Galactan Is Dependent on the Lipopolysaccharide O-Antigen

ABSTRACT Kingella kingae is a leading cause of bone and joint infections and other invasive diseases in young children. A key K. kingae virulence determinant is a secreted exopolysaccharide that mediates resistance to serum complement and neutrophils and is required for full pathogenicity. The K. ki...

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Main Authors: Nina R. Montoya, Eric A. Porsch, Vanessa L. Muñoz, Artur Muszyński, Jiri Vlach, David K. Hahn, Parastoo Azadi, Matthew Sherman, Hyojik Yang, Courtney E. Chandler, Robert K. Ernst, Joseph W. St. Geme
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02295-22