Deep learning enhancing guide RNA design for CRISPR/Cas12a‐based diagnostics

Deep learning enhancing guide RNA design for CRISPR/Cas12a‐based diagnostics

Abstract Rapid and accurate diagnostic tests are fundamental for improving patient outcomes and combating infectious diseases. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Cas12a‐based detection system has emerged as a promising solution for on‐site nucleic acid testing. No...

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Bibliographic Details
Main Authors: Baicheng Huang, Ling Guo, Hang Yin, Yue Wu, Zihan Zeng, Sujie Xu, Yufeng Lou, Zhimin Ai, Weiqiang Zhang, Xingchi Kan, Qian Yu, Shimin Du, Chao Li, Lina Wu, Xingxu Huang, Shengqi Wang, Xinjie Wang
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:iMeta
Subjects:
Cas12a
CRISPR
crRNA design
convolutional neural network
deep learning
diagnostic
Online Access:https://doi.org/10.1002/imt2.214

Internet

https://doi.org/10.1002/imt2.214

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