Agomelatine, Ketamine and Vortioxetine Attenuate Energy Cell Metabolism—In Vitro Study

Agomelatine, Ketamine and Vortioxetine Attenuate Energy Cell Metabolism—In Vitro Study

This determination of the mitochondrial effect of pharmacologically different antidepressants (agomelatine, ketamine and vortioxetine) was evaluated and quantified in vitro in pig brain-isolated mitochondria. We measured the activity of mitochondrial complexes, citrate synthase, malate dehydrogenase...

Full description

Bibliographic Details
Main Authors: Matej Ľupták, Zdeněk Fišar, Jana Hroudová
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative phosphorylation
mitochondrial respiration
reactive oxygen species
ATP
monoamine oxidase
antidepressants
Online Access:https://www.mdpi.com/1422-0067/23/22/13824

Internet

https://www.mdpi.com/1422-0067/23/22/13824

Similar Items