PACAP Modulates the Autophagy Process in an In Vitro Model of Amyotrophic Lateral Sclerosis

PACAP Modulates the Autophagy Process in an In Vitro Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of complex etiology leading to motor neuron degeneration. Many gene alterations cause this pathology, including mutation in Cu, Zn superoxide dismutase (SOD1), which leads to its gain of function. Mutant SOD1 proteins are...

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Bibliographic Details
Main Authors: Agata Grazia D’Amico, Grazia Maugeri, Salvatore Saccone, Concetta Federico, Sebastiano Cavallaro, Dora Reglodi, Velia D’Agata
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
PACAP
ALS
autophagy process
hypoxia condition
Online Access:https://www.mdpi.com/1422-0067/21/8/2943

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https://www.mdpi.com/1422-0067/21/8/2943

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