Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols

Sulfenamides are organosulfur reagents that feature labile S–N bonds and have potential applications in chemical synthesis. Here, the authors report the preparation of N-acyl sulfenamides via copper-catalyzed S-amidation of thiols with dioxazolones; These N-acyl sulfenamides can be used to prepare u...

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Bibliographic Details
Main Authors: Ziqian Bai, Shiyang Zhu, Yiyao Hu, Peng Yang, Xin Chu, Gang He, Hao Wang, Gong Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34223-7