Vitamin D3 Priming of Dendritic Cells Shifts Human Neutrophil-Dependent Th17 Cell Development to Regulatory T Cells

Vitamin D3 Priming of Dendritic Cells Shifts Human Neutrophil-Dependent Th17 Cell Development to Regulatory T Cells

Vitamin D3 (VD3) is a potential adjuvant for use in tolerogenic vaccine formulations that target dendritic cells (DCs) for the treatment of chronic inflammatory disorders, e.g., autoimmune diseases. These disorders are often associated with enhanced activity of IL-17-producing T helper 17 (Th17) cel...

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Bibliographic Details
Main Authors: Florianne M. J. Hafkamp, Esther W. M. Taanman-Kueter, Toni M. M. van Capel, Tom Groot Kormelink, Esther C. de Jong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
vitamin D3
dendritic cells
neutrophils
Th17 cells
Treg
autoimmune disorders
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.872665/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.872665/full

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