Ellagic acid ameliorates arsenic-induced neuronal ferroptosis and cognitive impairment via Nrf2/GPX4 signaling pathway

Ellagic acid ameliorates arsenic-induced neuronal ferroptosis and cognitive impairment via Nrf2/GPX4 signaling pathway

Arsenic, a neurotoxic metalloid, poses significant health risks. However, ellagic acid, renowned for its antioxidant properties, has shown potential in neuroprotection. This study aimed to investigate the neuroprotective effects of ellagic acid against arsenic-induced neuronal ferroptosis and cognit...

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Bibliographic Details
Main Authors: Xiyue Yang, Fang Chu, Zhe Jiao, Hao Yu, Wenjing Yang, Yang Li, Chunqing Lu, Hao Ma, Sheng Wang, Zhipeng Liu, Shaoxiao Qin, Hongna Sun
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Arsenic
Ellagic acid
Ferroptosis
Nuclear factor E2-related factor 2
Glutathione peroxidase 4
Hippocampal neuron
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324009096

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http://www.sciencedirect.com/science/article/pii/S0147651324009096

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