Quick synthesis of isatin-derived knoevenagel adducts using only eco-friendly solvent

A variety of knoevenagel compounds from isatin were synthesized using an eco-friendly methodology. It was used only the binary solvent ethanol: water (3:7 v/v) without the presence of metal catalyst what enabled the reaction between different isatins with malononitrile in a quick reaction time of 2–...

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Bibliographic Details
Main Authors: João Marcos Gomes de Oliveira Ferreira, Girlyanderson Araújo da Silva, Maísa Cavalcanti Coelho, Claudio Gabriel Lima Junior, Juliana Alves Vale
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715621000400