Experimental observation of the sequence of tibial plateau chondrocyte and matrix degeneration in spontaneous osteoarthritis in Guinea pigs

Abstract Background To observe the sequence of chondrocyte degeneration and matrix degradation in the superficial surface cartilage of the tibial plateau in guinea pigs with spontaneous knee osteoarthritis (OA). Methods Sixty guinea pigs were euthanized at the ages of 8 months (n = 20),10 months (n ...

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Bibliographic Details
Main Authors: Xiao-jian Wang, Lei Wei, Yan Xue, Rong-shan Li
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Musculoskeletal Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12891-021-04281-x