Experimental observation of the sequence of tibial plateau chondrocyte and matrix degeneration in spontaneous osteoarthritis in Guinea pigs
Abstract Background To observe the sequence of chondrocyte degeneration and matrix degradation in the superficial surface cartilage of the tibial plateau in guinea pigs with spontaneous knee osteoarthritis (OA). Methods Sixty guinea pigs were euthanized at the ages of 8 months (n = 20),10 months (n ...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | BMC Musculoskeletal Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12891-021-04281-x |