Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology

Yu et al. identify marked differences in the telomere and immunologic profiles of neuroblastoma cell lines displaying MES and ADRN lineage characteristics. They show that pharmacologically converting ADRN into MES cells triggers associated switch in telomere/immunologic protein profiles whereas inhi...

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Bibliographic Details
Main Authors: Eun Young Yu, Syed S. Zahid, Sarah Aloe, Erik Falck-Pedersen, Xi Kathy Zhou, Nai-Kong V. Cheung, Neal F. Lue
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02821-8