Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice

Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice

Microbiome composition and function have been implicated as contributing factors in the pathogenesis of autoimmune diseases (ADs), including systemic lupus erythematosus (SLE), rheumatoid arthritis and autoimmune hepatitis (AIH). Furthermore, dysbiosis of gut microbiome is associated with impaired b...

Full description

Bibliographic Details
Main Authors: Hui Wang, Gangduo Wang, Nivedita Banerjee, Yuejin Liang, Xiaotang Du, Paul J. Boor, Kristi L. Hoffman, M. Firoze Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
microbiome
oxidative stress
permeability
inflammation
autoimmunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.651191/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.651191/full

Similar Items