Selective suppression of antisense transcription by Set2-mediated H3K36 methylation

Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.

Bibliographic Details
Main Authors: Swaminathan Venkatesh, Hua Li, Madelaine M. Gogol, Jerry L. Workman
Format: Article
Language:English
Published: Nature Portfolio 2016-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13610