Selective suppression of antisense transcription by Set2-mediated H3K36 methylation
Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2016-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms13610 |
| _version_ | 1819194743380246528 |
|---|---|
| author | Swaminathan Venkatesh Hua Li Madelaine M. Gogol Jerry L. Workman |
| author_facet | Swaminathan Venkatesh Hua Li Madelaine M. Gogol Jerry L. Workman |
| author_sort | Swaminathan Venkatesh |
| collection | DOAJ |
| description | Maintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes. |
| first_indexed | 2024-12-23T02:01:43Z |
| format | Article |
| id | doaj.art-1ef059dc47f940508d6d5a9b3cc1e47b |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-23T02:01:43Z |
| publishDate | 2016-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-1ef059dc47f940508d6d5a9b3cc1e47b2022-12-21T18:03:58ZengNature PortfolioNature Communications2041-17232016-11-017111410.1038/ncomms13610Selective suppression of antisense transcription by Set2-mediated H3K36 methylationSwaminathan Venkatesh0Hua Li1Madelaine M. Gogol2Jerry L. Workman3Stowers Institute for Medical ResearchStowers Institute for Medical ResearchStowers Institute for Medical ResearchStowers Institute for Medical ResearchMaintenance of chromatin structure in coding regions is partially dependent on transcription, with histone methyltransferase Set2 playing a role in this process. Here, the authors provide evidence that Set2 regulates repression of a specific set of antisense RNAs embedded within the coding genes.https://doi.org/10.1038/ncomms13610 |
| spellingShingle | Swaminathan Venkatesh Hua Li Madelaine M. Gogol Jerry L. Workman Selective suppression of antisense transcription by Set2-mediated H3K36 methylation Nature Communications |
| title | Selective suppression of antisense transcription by Set2-mediated H3K36 methylation |
| title_full | Selective suppression of antisense transcription by Set2-mediated H3K36 methylation |
| title_fullStr | Selective suppression of antisense transcription by Set2-mediated H3K36 methylation |
| title_full_unstemmed | Selective suppression of antisense transcription by Set2-mediated H3K36 methylation |
| title_short | Selective suppression of antisense transcription by Set2-mediated H3K36 methylation |
| title_sort | selective suppression of antisense transcription by set2 mediated h3k36 methylation |
| url | https://doi.org/10.1038/ncomms13610 |
| work_keys_str_mv | AT swaminathanvenkatesh selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation AT huali selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation AT madelainemgogol selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation AT jerrylworkman selectivesuppressionofantisensetranscriptionbyset2mediatedh3k36methylation |