GDNF family receptor alpha‐like antagonist antibody alleviates chemotherapy‐induced cachexia in melanoma‐bearing mice

GDNF family receptor alpha‐like antagonist antibody alleviates chemotherapy‐induced cachexia in melanoma‐bearing mice

Abstract Background Patients with cancer undergoing chemotherapy experience cachexia with anorexia, body weight loss, and the depletion of skeletal muscles and adipose tissues. Effective treatment strategies for chemotherapy‐induced cachexia are scarce. The growth differentiation factor 15 (GDF15)/G...

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Bibliographic Details
Main Authors: Beom Yong Lee, Jongwon Jeong, Inseong Jung, Hanchae Cho, Dokyung Jung, Jiwon Shin, Jun‐kook Park, Eunju Park, Soojeong Noh, Sanghee Shin, Sungmin Kang, Jong‐Ik Heo, Moon‐Chang Baek, Kyungmoo Yea
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Cancer cachexia
Chemotherapy
Cisplatin
GDF15
GFRAL
GFRAL antagonist antibody
Online Access:https://doi.org/10.1002/jcsm.13219

Internet

https://doi.org/10.1002/jcsm.13219

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