Monomeric, Oligomeric and Polymeric Proteins in Huntington Disease and Other Diseases of Polyglutamine Expansion
Huntington disease and other diseases of polyglutamine expansion are each caused by a different protein bearing an excessively long polyglutamine sequence and are associated with neuronal death. Although these diseases affect largely different brain regions, they all share a number of characteristic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-03-01
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Series: | Brain Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-3425/4/1/91 |