Pyroptosis, inflammasome, and gasdermins in tumor immunity

The gasdermins (GSDM), a family of pore-forming proteins, consist of gasdermin A (GSDMA), gasdermin B (GSDMB), gasdermin C (GSDMC), gasdermin D (GSDMD), gasdermin E (GSDME) and DFNB59 (Pejvakin (PJVK)) in humans. These proteins play an important role in pyroptosis. Among them, GSDMD is the most exte...

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Bibliographic Details
Main Authors: Xiaohu Ouyang, Junfen Zhou, Lan Lin, Zili Zhang, Shanshan Luo, Desheng Hu
Format: Article
Language:English
Published: SAGE Publishing 2023-01-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/17534259221143216