Impairment of adenosine signaling disrupts early embryo development: unveiling the underlying mechanisms

Impairment of adenosine signaling disrupts early embryo development: unveiling the underlying mechanisms

Purinergic signaling has been implicated in many biological functions, including development. In this study, we investigate the functions of extracellular adenosine and adenosine receptors using a mouse embryonic stem cell (ESC) line and morula stages isolated from mouse embryos. Feeder-free mouse E...

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Bibliographic Details
Main Authors: Talita Glaser, Patrícia Martins, Renata Beco, Carolina Adriane Bento, Angelica R. Cappellari, Sophia La Banca Oliveira, Christian Albert Merkel, Vanessa Fernandes Arnaud-Sampaio, Claudiana Lameu, Ana Maria Battastini, Henning Ulrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
purinergic signaling
ERK1/2
calcium signaling
embryonic stem cells
adenosine
caffeine
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1328398/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1328398/full

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