The endocannabinoid ARA-S facilitates the activation of cardiac Kv7.1/KCNE1 channels from different species

The endogenous endocannabinoid-like compound N-arachidonoyl-L-serine (ARA-S) facilitates activation of the human Kv7.1/KCNE1 channel and shortens a prolonged action potential duration and QT interval in guinea pig hearts. Hence, ARA-S is interesting to study further in cardiac models to explore the...

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Bibliographic Details
Main Authors: Irene Hiniesto-Iñigo, Veronika A. Linhart, Ali S. Kusay, Sara I. Liin
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Channels
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19336950.2024.2420651