Double emulsion-pretreated microwell culture for the in vitro production of multicellular spheroids and their in situ analysis

Abstract Multicellular spheroids have served as a promising preclinical model for drug efficacy testing and disease modeling. Many microfluidic technologies, including those based on water–oil–water double emulsions, have been introduced for the production of spheroids. However, sustained culture an...

Full description

Bibliographic Details
Main Authors: Fuyang Qu, Shirui Zhao, Guangyao Cheng, Habibur Rahman, Qinru Xiao, Renee Wan Yi Chan, Yi-Ping Ho
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-021-00267-w