The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cells.

The ganglioside GM3 is associated with cisplatin-induced apoptosis in human colon cancer cells.

Cisplatin (cis-diamminedichloroplatinum, CDDP) is a well-known chemotherapeutic agent for the treatment of several cancers. However, the precise mechanism underlying apoptosis of cancer cells induced by CDDP remains unclear. In this study, we show mechanistically that CDDP induces GM3-mediated apopt...

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Bibliographic Details
Main Authors: Tae-Wook Chung, Hee-Jung Choi, Seok-Jo Kim, Choong-Hwan Kwak, Kwon-Ho Song, Un-Ho Jin, Young-Chae Chang, Hyeun Wook Chang, Young-Choon Lee, Ki-Tae Ha, Cheorl-Ho Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020741?pdf=render

Internet

http://europepmc.org/articles/PMC4020741?pdf=render

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