Interferon-β signaling contributes to Ras transformation.

Increasing evidence has pointed to activated type I interferon signaling in tumors. However, the molecular basis for such activation and its role in tumorigenesis remain unclear. In the current studies, we report that activation of type I interferon (IFN) signaling in tumor cells is primarily due to...

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Bibliographic Details
Main Authors: Yu-Chen Tsai, Sidney Pestka, Lu-Hai Wang, Loren W Runnels, Shan Wan, Yi Lisa Lyu, Leroy F Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3163666?pdf=render