Single-cell analysis of T lymphocytes infiltrating colorectal carcinoma: the dilemma of specificity

Single-cell analysis of T lymphocytes infiltrating colorectal carcinoma: the dilemma of specificity

ABSTRACTAdvances in single-cell RNA and T cell receptor (TCR) sequencing allow to study the specificity and functionality of tumor-infiltrating T lymphocytes. A recent study unravels fundamental differences between microsatellite-instable (MSI) colorectal cancers, in which T cells tend to be tumor-s...

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Bibliographic Details
Main Authors: Manuela Lizarralde-Guerrero, Laura Zucaro, Guido Kroemer, Jonathan G. Pol
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:OncoImmunology
Subjects:
Colorectal cancer
microsatellite instability
single-cell transcriptomics
T cell receptor
tumor-infiltrating lymphocytes
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2300520

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2023.2300520

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