Higher tacrolimus trough levels and time in the therapeutic range are associated with the risk of acute rejection in the first month after renal transplantation

Higher tacrolimus trough levels and time in the therapeutic range are associated with the risk of acute rejection in the first month after renal transplantation

Abstract Background Tacrolimus trough levels (C0) are used in most transplant centres for therapeutic drug monitoring (TDM) of tacrolimus (Tac). The target range of Tac C0 has been remarkably changed, with a target as low as 3–7 ng/ml in the 2009 European consensus conference and a target of 4–12 ng...

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Bibliographic Details
Main Authors: Thi Van Anh Nguyen, Huu Duy Nguyen, Thi Lien Huong Nguyen, Viet Thang Le, Xuan Kien Nguyen, Viet Tien Tran, Dinh Tuan Le, Ba Thang Ta
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Nephrology
Subjects:
Acute rejection
Tacrolimus
Therapeutic drug monitoring
Time in therapeutic range
Renal transplantation
Vietnam
Online Access:https://doi.org/10.1186/s12882-023-03188-0

Internet

https://doi.org/10.1186/s12882-023-03188-0

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