Validation of Fucoxanthin from Microalgae <em>Phaeodactylum tricornutum</em> for the Detection of Amyloid Burden in Transgenic Mouse Models of Alzheimer’s Disease

The visualization of misfolded Aβ peptides by using fluorescence chemical dyes is very important in Alzheimer’s disease (AD) diagnosis. Here, we describe the fluorescent substance, fucoxanthin, which detects Aβ aggregates in the brain of AD transgenic mouse models. We found that fucoxanthin from the...

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Bibliographic Details
Main Authors: A-Hyeon Lee, Sung-Chul Hong, Inwook Park, Soljee Yoon, YoungSoo Kim, Jinsik Kim, Seung-Hoon Yang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/13/5878