Comparative hepatotoxicity of novel lithium bis(trifluoromethanesulfonyl)imide (LiTFSI, ie. HQ-115) and legacy Perfluorooctanoic acid (PFOA) in male mice: Insights into epigenetic mechanisms and pathway-specific responses

Comparative hepatotoxicity of novel lithium bis(trifluoromethanesulfonyl)imide (LiTFSI, ie. HQ-115) and legacy Perfluorooctanoic acid (PFOA) in male mice: Insights into epigenetic mechanisms and pathway-specific responses

Lithium Bis(trifluoromethanesulfonyl)imide (LiTFSI ie. HQ-115), a polymer electrolyte used in energy applications, has been detected in the environment, yet its health risks and environmental epigenetic effects remain unknown. This study aims to unravel the potential health risks associated with LiT...

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Bibliographic Details
Main Authors: Mia Sands, Xing Zhang, Arnon gal, Mary Laws, Michael Spinella, Zeynep-Madak Erdogan, Joseph Irudayaraj
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Environment International
Subjects:
PFAS
Lithium bis(trifluoromethanesulfonyl)imide (LiTFSI or HQ-115)
Perfluorooctanoic Acid (PFOA)
Hepatotoxicity
DNA methylation
Lipid metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412024001429

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http://www.sciencedirect.com/science/article/pii/S0160412024001429

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