Inhibition of Pyruvate Dehydrogenase in the Heart as an Initiating Event in the Development of Diabetic Cardiomyopathy

Inhibition of Pyruvate Dehydrogenase in the Heart as an Initiating Event in the Development of Diabetic Cardiomyopathy

Obesity affects a growing fraction of the population and is a risk factor for type 2 diabetes and cardiovascular disease. Even in the absence of hypertension and coronary artery disease, type 2 diabetes can result in a heart disease termed diabetic cardiomyopathy. Diminished glucose oxidation, incre...

Full description

Bibliographic Details
Main Authors: Abdallah Elnwasany, Heba A. Ewida, Pamela A. Szweda, Luke I. Szweda
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antioxidants
Subjects:
pyruvate dehydrogenase
diabetes
obesity
metabolic inflexibility
oxidative stress
cardiomyopathy
Online Access:https://www.mdpi.com/2076-3921/12/3/756

Internet

https://www.mdpi.com/2076-3921/12/3/756

Similar Items