Association of complement C3 inhibitor pegcetacoplan with reduced photoreceptor degeneration beyond areas of geographic atrophy

Abstract Preservation of photoreceptors beyond areas of retinal pigment epithelium atrophy is a critical treatment goal in eyes with geographic atrophy (GA) to prevent vision loss. Thus, we assessed the association of treatment with the complement C3 inhibitor pegcetacoplan with optical coherence to...

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Bibliographic Details
Main Authors: Maximilian Pfau, Steffen Schmitz-Valckenberg, Ramiro Ribeiro, Reza Safaei, Alex McKeown, Monika Fleckenstein, Frank G. Holz
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22404-9