Role of CD133/NRF2 Axis in the Development of Colon Cancer Stem Cell-Like Properties

Role of CD133/NRF2 Axis in the Development of Colon Cancer Stem Cell-Like Properties

Cancer stem cells (CSCs) exhibit intrinsic therapy/stress resistance, which often cause cancer recurrence after therapy. In this study, we investigated the potential relationship between the cluster of differentiation (CD)-133, a CSC marker of colon cancer, and nuclear factor erythroid 2-like 2 (NFE...

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Bibliographic Details
Main Authors: Jimin Park, Seung Ki Kim, Steffanus Pranoto Hallis, Bo-Hyun Choi, Mi-Kyoung Kwak
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
CD133
cancer stem cell
NRF2
PI3K/AKT/GSK-3β
sphere formation
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.808300/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.808300/full

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