Closed-loop controller based on reference signal tracking for absence seizures

Abstract Absent epilepsy is a kind of refractory epilepsy, which is characterized by 2–4 Hz spike and wave discharges (SWDs) in electroencephalogram. Open-loop deep brain stimulation (DBS) targeting the thalamic reticular nucleus (TRN) is an effective method to treat absent epilepsy by eliminating S...

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Bibliographic Details
Main Authors: Hudong Zhang, Yuting Chen, Yan Xie, Yuan Chai
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10803-x