The Quality Control of Midecamycin and the Predictive Demarcation between Its Impurities and Components

The Quality Control of Midecamycin and the Predictive Demarcation between Its Impurities and Components

Midecamycin is a 16-membered macrolide antibiotic. It can inhibit the synthesis of bacterial proteins by blocking up the activity of peptidyl transferase in the 50S ribosome. We used high-resolution mass spectrometry to analyze midecamycin, and quantitatively analyzed of each component of midecamyci...

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Bibliographic Details
Main Authors: Mingyan Yu, Weijian Wang, Wenkun Liu, Huiru Yang, Tong Sun, Haiyun Zhao, Dejun Chen
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Separations
Subjects:
macrolide
midecamycin
high-resolution mass spectrometry (HRMS)
molecular docking
Online Access:https://www.mdpi.com/2297-8739/9/8/225

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https://www.mdpi.com/2297-8739/9/8/225

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