SARM1 deletion in parvalbumin neurons is associated with autism-like behaviors in mice

Abstract Autism spectrum disorder (ASD), a group of neurodevelopmental disorder diseases, is characterized by social deficits, communication difficulties, and repetitive behaviors. Sterile alpha and TIR motif-containing 1 protein (SARM1) is known as an autism-associated protein and is enriched in br...

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Bibliographic Details
Main Authors: Ludan Xiang, Qian Wu, Huankun Sun, Xuemeng Miao, Zhaoting Lv, Huitao Liu, Lan Chen, Yanrou Gu, Jianjun Chen, Siyao Zhou, Huixia Jiang, Siyu Du, Yixin Zhou, Hui Dong, Yiren Fan, Shuangda Miao, Qi Lu, Liyun Chang, Hui Wang, Yi Lu, Xingxing Xu, Wei Wang, Zhihui Huang
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05083-2