The ginsenoside Rg2 downregulates MMP-1 expression in keratinocyte (HaCaT)-conditioned medium-treated human fibroblasts (Hs68)

The ginsenoside Rg2 downregulates MMP-1 expression in keratinocyte (HaCaT)-conditioned medium-treated human fibroblasts (Hs68)

Abstract Keratinocytes exposed to UVB induce the production of cytokines, which activate fibroblasts and increase the expression of matrix metalloproteinases (MMPs). The increased expression of MMPs leads to connective tissue damage and wrinkle formation, resulting in skin aging. In this study, we u...

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Bibliographic Details
Main Authors: Sol-ra Oh, Se-keun Park, Pyeongjae Lee, Yong-Min Kim
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Series:Applied Biological Chemistry
Subjects:
Keratinocyte-conditioned medium
MMP-1
MAPKs
Ginsenoside Rg2
Online Access:https://doi.org/10.1186/s13765-023-00843-w

Internet

https://doi.org/10.1186/s13765-023-00843-w

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