Role of Serotonin in the Maintenance of Inflammatory State in Crohn’s Disease

Role of Serotonin in the Maintenance of Inflammatory State in Crohn’s Disease

Crohn’s disease (CD) is a chronic intestinal inflammation considered to be a major entity of inflammatory bowel diseases (IBDs), affecting different segments of the whole gastrointestinal tract. Peripheral serotonin (5-HT), a bioactive amine predominantly produced by gut enterochromaffin cells (ECs)...

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Bibliographic Details
Main Authors: Simona Pergolizzi, Alessio Alesci, Antonio Centofanti, Marialuisa Aragona, Socrate Pallio, Ludovico Magaudda, Giuseppina Cutroneo, Eugenia Rita Lauriano
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
Crohn’s disease
serotonin
dendritic cells
myofibroblast
goblet cells
Online Access:https://www.mdpi.com/2227-9059/10/4/765

Internet

https://www.mdpi.com/2227-9059/10/4/765

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