Total flavonoids from Saussurea involucrata attenuate inflammation in lipopolysaccharide-stimulated RAW264.7 macrophages via modulating p65, c-Jun, and IRF3 signaling pathways

Total flavonoids from Saussurea involucrata attenuate inflammation in lipopolysaccharide-stimulated RAW264.7 macrophages via modulating p65, c-Jun, and IRF3 signaling pathways

Objective: To investigate the anti-inflammatory effects of the total flavonoids from Saussurea involucrata on lipopolysaccharides (LPS)-stimulated murine RAW264.7 macrophages and explore its underlying mechanism of action. Methods: Total flavonoids from Saussurea involucrata were extracted using chr...

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Bibliographic Details
Main Authors: Li-Shan Yan, Li Wang, Brian Chi-Yan Cheng, Yu Ding, Jing Kong, Qing Gao Wang, Xiu-Qiong Fu, Shuo-Feng Zhang, Gan Luo, Yi Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
saussurea involucrata; cytokines; proinflammatory; macrophages; flavonoids
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=6;spage=273;epage=284;aulast=Yan

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2021;volume=11;issue=6;spage=273;epage=284;aulast=Yan

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