The Cdk inhibitor dinaciclib as a promising anti-tumorigenic agent in biliary tract cancer

The Cdk inhibitor dinaciclib as a promising anti-tumorigenic agent in biliary tract cancer

Biliary tract cancer (BTC) is a rare malignancy with rising incidence. The therapeutic options are limited and the overall survival remains poor. Cyclin-dependent kinases, drivers of cell cycle and transcription have numerous biological functions and are known to be dysregulated in numerous tumor en...

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Bibliographic Details
Main Authors: Celina Ablinger, Daniel Neureiter, Theresa Mähr, Christian Mayr, Tobias Kiesslich, Nicole Maeding, Irina Valenta, Maximilian Ardelt, Fabian Wilhelm, Elen Neureiter, Markus Ritter, Johanna Pachmayr, Petra Huber-Cantonati
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Cancer Biology & Therapy
Subjects:
biliary tract cancer
Cdk
dinaciclib
cytotoxicity
apoptosis
3D cell culture
Online Access:https://www.tandfonline.com/doi/10.1080/15384047.2024.2439057

Internet

https://www.tandfonline.com/doi/10.1080/15384047.2024.2439057

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