Panax Notoginseng Saponins as a Novel Nature Stabilizer for Poorly Soluble Drug Nanocrystals: A Case Study with Baicalein

This study is aimed at seeking a nature saponin-based stabilizer for drug nanosuspensions. A poorly soluble drug (baicalein, BCL) was used as a model drug. BCL nanosuspensions with particle size of 156 nm were prepared by means of homogenization and converted into BCL nanocrystals (BCL-NC) stabilize...

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Bibliographic Details
Main Authors: Yuanbiao Xie, Yueqin Ma, Junnan Xu, Yang Liu, Pengfei Yue, Qin Zheng, Pengyi Hu, Ming Yang
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/9/1149