Deletion and down-regulation of HRH4 gene in gastric carcinomas: a potential correlation with tumor progression.

BACKGROUND: Histamine is an established growth factor for gastrointestinal malignancies. The effect of histamine is largely determined locally by the histamine receptor expression pattern. Histamine receptor H4 (HRH4), the newest member of the histamine receptor family, is positively expressed on th...

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Bibliographic Details
Main Authors: Chao Zhang, Yi Xiong, Jiana Li, Yang Yang, Li Liu, Wen Wang, Luo Wang, Manhui Li, Zhengyu Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3282702?pdf=render