Cholesterol and host cell surface proteins contribute to cell-cell fusion induced by the Burkholderia type VI secretion system 5.

Cholesterol and host cell surface proteins contribute to cell-cell fusion induced by the Burkholderia type VI secretion system 5.

Following escape into the cytoplasm of host cells, Burkholderia pseudomallei and the related species Burkholderia thailandensis employ the type VI secretion system 5 (T6SS-5) to induce plasma membrane fusion with an adjacent host cell. This process leads to the formation of multinucleated giant cell...

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Bibliographic Details
Main Authors: Liam Whiteley, Maria Haug, Kristina Klein, Matthias Willmann, Erwin Bohn, Salvatore Chiantia, Sandra Schwarz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5626464?pdf=render

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http://europepmc.org/articles/PMC5626464?pdf=render

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