Estimations of Mutation Rates Depend on Population Allele Frequency Distribution: The Case of Autosomal Microsatellites

Estimations of Mutation Rates Depend on Population Allele Frequency Distribution: The Case of Autosomal Microsatellites

Microsatellites (or short-tandem repeats (STRs)) are widely used in anthropology and evolutionary studies. Their extensive polymorphism and rapid evolution make them the ideal genetic marker for dating events, such as the age of a gene or a population. This usage requires the estimation of mutation...

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Bibliographic Details
Main Authors: Sofia Antão-Sousa, Eduardo Conde-Sousa, Leonor Gusmão, António Amorim, Nádia Pinto
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
microsatellites
STRs
autosomes
mutation rate estimates biases
hidden mutations
dating
Online Access:https://www.mdpi.com/2073-4425/13/7/1248

Internet

https://www.mdpi.com/2073-4425/13/7/1248

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