Synthesis of new 3-substituted quinolone derivatives with benzene sulfonamide group using hydrazine linker with their docking and antibacterial studies in vitro

Quinolones are among the prominent class of broad-spectrum antibiotics. In this work, a series of 1,4-dihydro-4-oxo-3-[3-{benzenesulfon}-2-hydrazino-1-oxo-]quinoline derivatives 6a-e were synthesized and tested for their antibacterial efficacy in vitro. Compounds 6a-e were characterized by NMR (1H,1...

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Bibliographic Details
Main Authors: Nishtha Saxena, Rakesh Kumar, Swapnil Shankhdhar, Nivedita Srivastava
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622001163