Synthesis of new 3-substituted quinolone derivatives with benzene sulfonamide group using hydrazine linker with their docking and antibacterial studies in vitro
Quinolones are among the prominent class of broad-spectrum antibiotics. In this work, a series of 1,4-dihydro-4-oxo-3-[3-{benzenesulfon}-2-hydrazino-1-oxo-]quinoline derivatives 6a-e were synthesized and tested for their antibacterial efficacy in vitro. Compounds 6a-e were characterized by NMR (1H,1...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
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Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622001163 |